Volunteers to be deliberately infected with COVID-19 in singapore study

NCT ID NCT06654973

Ongoing Knowledge-focused Sponsor: Tan Tock Seng Hospital Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study will safely give a small dose of the Delta COVID-19 virus to 20 healthy adults aged 21-30 in Singapore. The goal is to see if the virus causes infection and to check for side effects. This 'human challenge' model could help test future vaccines and treatments faster.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: SARS-CoV-2 Delta virus (intranasal drops)
What this could lead to: If successful, this model could speed up testing of new COVID-19 vaccines and treatments by safely infecting volunteers in a controlled setting.
What could go wrong: This is a very early safety and dose-finding study with only 20 people. It does not test any new treatment, and results may not apply to real-world infections.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

COVID-19

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COVID-19

Contacts and locations

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Locations

National Centre for Infectious Diseases

Singapore, Singapore, 308442, Singapore

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