Altitude training without the altitude: new hope for kidney disease fatigue?

This study tests whether breathing low-oxygen air during exercise (simulated high-altitude training) can improve walking ability and reduce fatigue in people with stage 3-4 chronic kidney disease. Sixty adults aged 40-65 will be split into three groups: simulated altitude training, regular aerobic training, or usual care. The goal is to see if this approach boosts exercise tolerance and quality of life better than standard exercise.