New device aims to clear lungs better in cystic fibrosis

NCT ID NCT04010253

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tested a device called Simeox, which helps clear mucus from the lungs, against a standard manual breathing technique (autogenic drainage) in 31 adults with cystic fibrosis. The goal was to see which method better improves lung function and eases symptoms like cough and congestion. Researchers measured lung function before and after each session to compare the two approaches.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Simeox device (airway clearance device)

What this could lead to

If it works, this could offer a more effective or easier way to clear mucus from the lungs in cystic fibrosis, potentially improving breathing and reducing symptoms.

What could go wrong

This is a small, completed study with only 31 participants, so results may not apply to everyone. The device may not work better than standard manual techniques.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cystic fibrosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CH Amiens

    Amiens, France

  • CH Nice

    Nice, France

  • CHRU Lille - Hopital Calmette

    Lille, France

  • CHU de Rouen

    Rouen, France

  • GH Sud - Hospices Civils de Lyon

    Lyon, France

  • Hopital Larrey

    Toulouse, France

  • Hôpital la Bocage CHRU de Dijon

    Dijon, France

  • Soins de Suite Nutritionnels et Respiratoires -Fondation IDLYS

    Roscoff, France