New device aims to clear lungs better in cystic fibrosis

NCT ID NCT04010253

Completed Symptom relief Sponsor: Association Nationale pour les Traitements A Domicile, les Innovations et la Recherche Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tested a device called Simeox, which helps clear mucus from the lungs, against a standard manual breathing technique (autogenic drainage) in 31 adults with cystic fibrosis. The goal was to see which method better improves lung function and eases symptoms like cough and congestion. Researchers measured lung function before and after each session to compare the two approaches.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Simeox device (airway clearance device)
What this could lead to: If it works, this could offer a more effective or easier way to clear mucus from the lungs in cystic fibrosis, potentially improving breathing and reducing symptoms.
What could go wrong: This is a small, completed study with only 31 participants, so results may not apply to everyone. The device may not work better than standard manual techniques.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cystic fibrosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CYSTIC FIBROSIS

Contacts and locations

Locations

CH Amiens

Amiens, France
CH Nice

Nice, France
CHRU Lille - Hopital Calmette

Lille, France
CHU de Rouen

Rouen, France
GH Sud - Hospices Civils de Lyon

Lyon, France
Hopital Larrey

Toulouse, France
Hôpital la Bocage CHRU de Dijon

Dijon, France
Soins de Suite Nutritionnels et Respiratoires -Fondation IDLYS

Roscoff, France

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