New Lung-Clearing device could ease breathing for kids with cystic fibrosis

NCT ID NCT04084041

Completed Symptom relief Sponsor: Physio-Assist Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tested a new device called Simeox, which helps clear mucus from the lungs, in 40 children with cystic fibrosis aged 8 to 18. Each child used the device for one month and standard chest physiotherapy for another month, in random order. The goal was to see if the device improves lung function and quality of life compared to the usual therapy.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Simeox airway clearance device
What this could lead to: If it works, this could offer a more effective or easier way for children with cystic fibrosis to clear mucus from their lungs, potentially improving breathing and reducing infections.
What could go wrong: This is a small, early-stage crossover study with only 40 children. The device may not prove better than standard physiotherapy, and results may not apply to all patients. No serious risks are expected, but the device may be uncomfortable or hard to use.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cystic fibrosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AIRWAY CLEARANCE IMPAIRMENT CYSTIC FIBROSIS IN CHILDREN

Contacts and locations

Locations

IMiD

Warsaw, Poland

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