New drug combo offers hope for hard-to-treat head and neck cancer

NCT ID NCT05054439

Ongoing Disease control Sponsor: Sichuan Baili Pharmaceutical Co., Ltd. Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated Apr 29, 2026 · Updated 24 times

Summary

This study tests a new drug called SI-B001 combined with paclitaxel in people with head and neck cancer that has come back or spread. It is for patients whose cancer worsened after standard treatments like immunotherapy or chemotherapy. The goal is to see if the combination shrinks tumors and is safe. About 42 adults will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Hunan Cancer Hospital

Changsha, Hunan, China
Shanghai Oriental Hospital

Shanghai, Shanghai Municipality, 200120, China
The Affiliated Cancer Hospital of Guizhou Medical University

Guiyang, Guizhou, China
The Second Affiliated Hospital of Guilin Medical University

Guilin, Guangxi, China
Union Hospital Tongji Medical College， Huazhong University of Science and Technology

Wuhan, Hubei, China
West China Hospital，Sichuan University

Chengdu, Sichuan, China
Zhejiang Cancer Hospital

Hangzhou, Zhejiang, China

Conditions

Explore the condition pages connected to this study.

HEAD AND NECK SQUAMOUS CELL CARCINOMA HEAD AND NECK SQUAMOUS CELL CARCINOMA