New hope for tough lymphoma: phase 3 trial pits SHR2554 against standard drug

NCT ID NCT06122389

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 3 trial compares a new drug called SHR2554 to an existing drug, chidamide, in 130 people with a rare type of lymphoma (PTCL) that has come back or not responded to at least one prior treatment. The main goal is to see if SHR2554 can delay cancer growth better than chidamide. Participants will receive either SHR2554 or chidamide, plus a dummy version of the other drug, so neither they nor their doctors know which they are getting.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

SHR2554 (a drug being tested) and chidamide (a standard drug)

What this could lead to

If SHR2554 works better than chidamide, it could offer a new treatment option for people with PTCL that has come back or not responded to prior therapy.

What could go wrong

This is a phase 3 trial, but it is still experimental. The new drug may not prove superior to the existing drug, and side effects are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

mature T-cell and NK-cell non-Hodgkin lymphoma Recurrence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Peking University Cancer Hospital

    RECRUITING

    Beijing, Beijing Municipality, 100000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••