New oral cancer drug enters first human safety trial

NCT ID NCT06484985

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-stage study tests a new oral drug, AXT-1003, in 78 people with advanced non-Hodgkin lymphoma or solid tumors that have not responded to standard treatments. The main goal is to check safety and find the right dose. Researchers will also look for signs that the drug shrinks tumors, but this is not yet a test of effectiveness.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

AXT-1003 (an oral capsule)

What this could lead to

If successful, this could point toward a new treatment option for people with advanced cancers that have not responded to standard therapies.

What could go wrong

This is a very early Phase 1 trial focused on safety, not effectiveness. It is small (78 people) and may not lead to a working treatment. Side effects are unknown.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

mature T-cell and NK-cell non-Hodgkin lymphoma neoplasm non-Hodgkin lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Beijing Cancer Hospital

    RECRUITING

    Beijing, China

  • Fudan University Shanghai Cancer Center

    RECRUITING

    Shanghai, China

  • Fujian Cancer Hospital

    RECRUITING

    Fuzhou, China

  • Hunan Cancer Hosptial

    RECRUITING

    Changsha, China

  • Sun Yat-Sen University Cancer Center

    RECRUITING

    Guangzhou, China