New antibody SHR-1707 tested in early Alzheimer's – safety first

NCT ID NCT05681819

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage trial tested an experimental drug called SHR-1707 in 33 people with mild memory problems or mild Alzheimer's disease. The drug is an antibody given through a vein, designed to target and clear amyloid plaques in the brain. The main goal was to check safety and side effects, while also measuring changes in brain amyloid levels.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

SHR-1707 (an experimental antibody given intravenously)

What this could lead to

If successful, this could point toward a treatment that slows Alzheimer's by clearing amyloid plaques from the brain.

What could go wrong

This is a very early Phase 1 safety study with only 33 people. It is not designed to prove the drug works, and many early Alzheimer's drugs fail in later trials.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ALZHEIMER S DISEASE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Alzheimer disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • The First Affiliated Hospital Of USTC

    Hefei, Anhui, 230001, China