New antibody SHR-1707 tested in early Alzheimer's – safety first
NCT ID NCT05681819
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-stage trial tested an experimental drug called SHR-1707 in 33 people with mild memory problems or mild Alzheimer's disease. The drug is an antibody given through a vein, designed to target and clear amyloid plaques in the brain. The main goal was to check safety and side effects, while also measuring changes in brain amyloid levels.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- SHR-1707 (an experimental antibody given intravenously)
- What this could lead to
- If successful, this could point toward a treatment that slows Alzheimer's by clearing amyloid plaques from the brain.
- What could go wrong
- This is a very early Phase 1 safety study with only 33 people. It is not designed to prove the drug works, and many early Alzheimer's drugs fail in later trials.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
The First Affiliated Hospital Of USTC
Hefei, Anhui, 230001, China
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