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Frozen shoulder: ultrasound gel or muscle exercises — which works better?

NCT ID NCT05475639

Symptom relief Sponsor: Cairo University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 08, 2026 · Last updated Jul 09, 2026 · Updated 1 time

Summary

This study compares two treatments for frozen shoulder (adhesive capsulitis): applying an anti-inflammatory gel through ultrasound (phonophoresis) versus a muscle relaxation exercise technique (post-isometric facilitation). About 45 adults aged 30–40 with the second stage of frozen shoulder will receive one of these treatments or standard physiotherapy three times a week for four weeks. Researchers will measure pain, pressure sensitivity, shoulder movement, and daily function to see which approach provides more relief.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Diclofenac gel (Voltaren) delivered via ultrasound
What this could lead to
If one treatment proves more effective, it could offer a simpler, drug-free option or a more targeted way to deliver pain relief for frozen shoulder.
What could go wrong
This is a small, early-stage study with only 45 participants, so results may not apply to everyone. Both treatments are generally safe but may not work for all cases.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

45 people

The number who actually took part.

Started

Jul 2025

Finished

Oct 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

30 to 40 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * The patient age will range from 30to 40years old from both sexes (male and female). * All recruited subjects in the 2nd stage of adhesive capsulitis (transitional stage). * The patient will be diagnosed and referred by orthopedist as Adhesive capsulitis. * The diagnosis will be confirmed by shoulder MRI. * The diagnosis will be confirmed by shrug test. * The patient will be referred by anterior shoulder pain or anterolateral shoulder pain. * Inclusion requirement include two or more of the following pain complaints: Grooming ones hair, Scratching your back and getting dressed, Overhead activities or Difficulty in the action of throwing the ball and giving a high -five. * All patients will sign the informed consent before joining the study. Exclusion Criteria: * Previous fracture with or without internal fixation in the shoulder joint * Any previous surgery in the shoulder joint and patient with tendon calcification * Local corticosteroid injection to the affected shoulder within the last three months or recent ones (Michener et al, 2004). * Neuromuscular disease * Rotator cuff tear * History of metastatic cancer or diagnosis of cancer within 12 months * Unstable angina

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Conditions

The condition(s) this trial relates to.

bursitis frozen shoulder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Adhesive capsulitis of shoulder

Contacts and locations

Locations

  • Out patient clinic of faculty of physical therapy

    Cairo, Egypt

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