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Gentle organ mobilization may ease frozen shoulder pain

NCT ID NCT07704411

Symptom relief Sponsor: Istanbul Medeniyet University Source: ClinicalTrials.gov ↗

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 15, 2026 · Last updated Jul 16, 2026 · Updated 1 time

Summary

This study investigates whether adding osteopathic visceral manipulation (OVM) — gentle mobilization of the liver and diaphragm — to a standard physical therapy program can reduce pain, improve range of motion, and lessen disability in people with right shoulder adhesive capsulitis (frozen shoulder). About 50 adults aged 40–65 with right-sided frozen shoulder will receive either OVM or a sham touch once a week for three weeks, alongside daily physical therapy. Researchers will measure pain, shoulder function, and movement before and after treatment.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
osteopathic visceral manipulation (liver and diaphragm mobilization)
What this could lead to
If effective, adding this hands-on technique to standard therapy could offer a non-drug way to reduce pain and improve shoulder movement in frozen shoulder.
What could go wrong
This is a small, early-stage trial with 49 participants, so results may not apply widely. The sham group also received physical therapy, making it hard to isolate the manipulation's effect.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

56 people

The number who actually took part.

Started

Jan 2023

Finished

Mar 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age between 18 and 65 years * Presence of pain originating from the right shoulder region persisting for at least 6 weeks * Availability of two-view shoulder radiographs obtained prior to the study to exclude causes of shoulder pain other than AC * No local corticosteroid injection for shoulder pain within the previous 6 months * No physical therapy administered for shoulder pain within the previous 6 months * No use of non-steroidal anti-inflammatory drugs (NSAIDs) during the study period * Availability of laboratory assessments including: * Complete blood count (CBC) * Erythrocyte sedimentation rate (ESR) * Liver function tests (AST, ALT) * C-reactive protein (CRP) * Pain intensity score of at least 4 cm on the Visual Analog Scale (VAS, 0-10 cm) Exclusion Criteria: * History of shoulder fracture on the affected side * Prior shoulder surgery * History of traumatic shoulder instability (subluxation or dislocation) * History of shoulder or visceral organ surgery within the past 6 months * History of systemic or inflammatory disease or malignancy * Presence of metabolic or endocrine bone disease * Pregnancy * Neurological disorders affecting upper extremity function * Psychiatric disorders that could interfere with treatment compliance or symptom evaluation * Use of antiplatelet medication * Previous osteopathic treatment

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Conditions

The condition(s) this trial relates to.

bursitis frozen shoulder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Osteopathic manipulative treatment (OMT) Shoulder adhesive capsulitis

Contacts and locations

Locations

  • Goztepe Suleyman Yalcin Sehir Hastanesi Fiziksel Tıp ve Rehabilitasyon Klinigi

    Istanbul, Turkey (Türkiye)

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