Could a shorter drug course work just as well for older AML patients?

NCT ID NCT07437950

First seen Feb 28, 2026 · Last updated Apr 28, 2026 · Updated 11 times

Summary

This study looks at whether giving the drug venetoclax for a shorter time, along with the combination drug ASTX727, is as effective as the usual longer course for adults aged 60 and older with newly diagnosed acute myeloid leukemia (AML) who cannot tolerate intensive chemotherapy. About 126 participants will be randomly assigned to one of two treatment schedules. The goal is to see if the shorter treatment can achieve similar rates of deep remission with fewer side effects.

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