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Can a 4-Month TB regimen work as well as 6 months?

NCT ID NCT06153069

Recruiting now Disease control Sponsor: Huashan Hospital Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether people with asymptomatic tuberculosis (TB) can be treated effectively with a shorter course of standard antibiotics—17 weeks instead of the usual 6 months. Researchers will compare the shorter regimen to standard treatment in 426 participants in China. The goal is to see if the shorter course can achieve similar cure rates without increasing the risk of relapse.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
isoniazid, rifampicin, pyrazinamide, ethambutol, rifapentine, moxifloxacin
What this could lead to
If successful, this could shorten tuberculosis treatment from the standard 6 months to about 4 months, making it easier for patients to complete therapy and reducing the burden on healthcare systems.
What could go wrong
This is a Phase 4 trial, but it focuses on asymptomatic TB, which is less studied. Shorter treatment may increase relapse risk, and results may not apply to symptomatic TB or other populations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

latent tuberculosis infection tuberculosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

TUBERCULOSIS

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Beijing Chest Hospital, Capital Medical University

    RECRUITING

    Beijing, Beijing Municipality, 200040, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Huashan Hospital of Fudan University

    ACTIVE_NOT_RECRUITING

    Shanghai, Shanghai Municipality, 200040, China

  • Liupanshui City Third People's Hospital

    RECRUITING

    Liupanshui, Guizhou, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Nayong County People's Hospital

    RECRUITING

    Nayong, Guizhou, 200040, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First People's Hospital of Linping District, Hangzhou

    RECRUITING

    Hangzhou, Zhejiang, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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