Shorter hormone therapy plus precision radiation may keep high-risk prostate cancer from spreading

NCT ID NCT05100472

First seen Nov 05, 2025 · Last updated May 15, 2026 · Updated 23 times

Summary

This study tests whether a shorter course of hormone therapy (ADT) combined with two types of radiation (brachytherapy and external beam) can safely prevent high-risk prostate cancer from coming back or spreading. About 50 men with aggressive prostate cancer and a favorable genetic score will take part. The goal is to see if this shorter, more intense treatment is effective while reducing side effects.

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Contacts and locations

Locations

  • Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities)

    Basking Ridge, New Jersey, 07920, United States

  • Memorial Sloan Kettering Bergen (Limited Protocol Activities)

    Montvale, New Jersey, 07645, United States

  • Memorial Sloan Kettering Cancer Center (All Protocol Activities)

    New York, New York, 10065, United States

  • Memorial Sloan Kettering Monmouth (Limited Protocol Activities)

    Middletown, New Jersey, 07748, United States

  • Memorial Sloan Kettering Nassau (Limited Protocol Activities)

    Uniondale, New York, 11553, United States

  • Memorial Sloan Kettering Suffolk - Commack (Limited Protocol Activities)

    Commack, New York, 11725, United States

  • Memorial Sloan Kettering Westchester (Limited Protocol Activities)

    Harrison, New York, 10604, United States

Conditions

Explore the condition pages connected to this study.