New combo therapy aims to wipe out rectal cancer before surgery

NCT ID NCT04928807

First seen Feb 28, 2026 · Last updated May 12, 2026 · Updated 12 times

Summary

This phase 3 trial tests whether a short course of radiation followed by immunotherapy (camrelizumab) and chemotherapy can completely eliminate rectal cancer before surgery. About 230 adults with locally advanced rectal cancer will be randomly assigned to this new approach or standard long-course chemoradiation. The main goal is to see if more patients have no cancer left in their removed tissue.

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Contacts and locations

Locations

  • Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

    Wuhan, Hubei, China

Conditions

Explore the condition pages connected to this study.