Can deeper anesthesia shield the heart during bypass surgery?

NCT ID NCT07770269

NEW Recruiting now Knowledge-focused Sponsor: AHEPA University Hospital Source: ClinicalTrials.gov ↗

First seen Aug 18, 2026 · Last updated Aug 18, 2026

Summary

This study looks at how the depth of anesthesia during cardiac surgery might influence heart function. Adults having elective on-pump heart surgery are randomly assigned to either standard or deeper anesthesia, guided by a brain monitor. Doctors measure heart performance using ultrasound and pressure readings at key points during the operation, and then track recovery over a year. The goal is to see if anesthesia depth affects how well the heart pumps after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Two levels of anesthesia depth guided by the Bispectral Index (BIS): standard (45-55) versus deeper (30-35), using propofol and remifentanil.
What this could lead to: If successful, this could help tailor anesthesia depth during cardiac surgery to better protect heart function and improve recovery.
What could go wrong: This is a small, early-stage study, so results may not apply broadly. Deeper anesthesia could carry risks, and the findings may not change clinical practice.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Cardiac Output, Low

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CARDIAC FUNCTION CARDIAC SURGERY PERIOPERATIVE CARDIAC DYSFUNCTION

Contacts and locations

Locations

AHEPA University General Hospital of Thessaloniki
RECRUITING

Thessaloniki, 54636, Greece

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