New 6-in-1 shot for babies shows promise in thai trial

NCT ID NCT04429295

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tested a new combination vaccine called Shan6™, which protects against six diseases (diphtheria, tetanus, whooping cough, hepatitis B, Hib, and polio) in healthy infants and toddlers in Thailand. The trial involved 460 participants and compared Shan6™ to a similar 5-in-1 vaccine given with separate polio shots. The goal was to see if Shan6™ works just as well and is safe when given alongside routine childhood vaccines.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Shan6™ (6-in-1 vaccine against diphtheria, tetanus, pertussis, hepatitis B, Hib, and polio)

What this could lead to

If successful, this could provide a simpler 6-in-1 vaccine option for infants, reducing the number of shots needed.

What could go wrong

This is a completed Phase 3 trial, so results are already in. The main risk is that the vaccine may not be as effective or safe as the current separate vaccines, but the study aims to show it is non-inferior.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

diphtheria prevention target hepatitis B virus infection prevention target pertussis prevention target pneumococcal infection prevention target poliomyelitis prevention target Rotavirus infection prevention target tetanus prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Investigational Site Number 7640001

    Bangkok, 10700, Thailand

  • Investigational Site Number 7640002

    Khon Kaen, 4002, Thailand

  • Investigational Site Number 7640003

    Bangkok, 10330, Thailand