New cocktail aims to tackle tough liver cancer

NCT ID NCT07392866

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new combination of drugs (SH006 plus chemotherapy) against the standard drug regorafenib in 120 people with advanced liver cancer that has not responded to immunotherapy. The goal is to see if the new combo can slow cancer growth or improve survival. Participants will be randomly assigned to one of the two treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

SH006 (a drug similar to bevacizumab) combined with oxaliplatin, capecitabine, and bevacizumab

What this could lead to

If successful, this combination could offer a new treatment option for people with advanced liver cancer who have already tried immunotherapy.

What could go wrong

This is an early-to-mid stage trial with only 120 participants. The new combination may not be more effective than the existing drug regorafenib, and side effects could be significant.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

hepatocellular carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Nanjing Tianyinshan Hospital

    Nanjing, Jiangsu, 211199, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Zhongshan Hospital, Fudan University

    Shanghai, Shanghai Municipality, 200032, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact