Could a diabetes pill boost heart and muscle health in kidney patients?

NCT ID NCT07060417

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This Phase 2 study will test whether empagliflozin (Jardiance), a drug already used for diabetes, can improve blood vessel health and exercise tolerance in 52 veterans with non-diabetic chronic kidney disease. Participants will take either the drug or a placebo for a period, and researchers will measure changes in artery function and leg blood flow. The goal is to see if this medication offers benefits beyond blood sugar control.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Empagliflozin (Jardiance)

What this could lead to

If successful, this could show that empagliflozin helps protect blood vessels and improve physical function in people with chronic kidney disease who do not have diabetes.

What could go wrong

This is a small, early-stage trial with only 52 participants, so results may not apply to everyone. It is also testing effects on blood vessel function rather than hard outcomes like kidney failure.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

chronic kidney disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • VA Salt Lake City Health Care System, Salt Lake City, UT

    Salt Lake City, Utah, 84148-0001, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact