Can a flash of light reveal how well angioplasty restores blood flow in diabetic feet?

NCT ID NCT07097857

First seen Aug 18, 2026 ยท Last updated Aug 18, 2026

Summary

This study explores whether a non-invasive imaging technique called spatial frequency domain imaging (SFDI) can measure changes in blood flow in the feet of people with diabetes who are undergoing angioplasty to treat peripheral arterial disease. Researchers will use SFDI to measure tissue oxygen saturation in the treated foot before and after the procedure, and compare these readings with standard toe pressure measurements. If SFDI works well, it could become a simple, painless way to evaluate the success of revascularization in diabetic patients.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Spatial frequency domain imaging (SFDI), a non-invasive light-based imaging technique
What this could lead to
If SFDI proves reliable, it could offer a quick, non-invasive way to assess blood flow in diabetic feet before and after angioplasty, potentially improving treatment decisions.
What could go wrong
This is a very small early study (15 participants), so results may not apply broadly. SFDI is experimental for this use, and its accuracy compared to standard methods is still uncertain.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Singapore General Hospital

    Singapore, SG, 169856, Singapore

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