Hormones and asthma: scientists probe why women suffer more

NCT ID NCT01759186

Ongoing Knowledge-focused Sponsor: The Cleveland Clinic Source: ClinicalTrials.gov ↗

First seen Jul 07, 2026 · Last updated Jul 08, 2026 · Updated 1 time

Summary

This research program investigates why severe asthma affects more women than men in adulthood, while the opposite is true in childhood. Researchers will study biological and chemical differences, including the role of menstrual cycles, to understand these patterns. The goal is to develop better tests to identify asthma types and track how the disease changes over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this research could lead to better diagnostic tests and personalized treatments for severe asthma based on gender and hormonal factors.
What could go wrong: This is an observational study, not a treatment trial. It may not directly result in new therapies, and findings may take years to translate into clinical practice.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

asthma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ASTHMA

Contacts and locations

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Locations

Cleveland Clinic

Cleveland, Ohio, 44195, United States
Rainbow Babies and Children's Hospital

Cleveland, Ohio, 44106, United States
University of Virginia

Charlottesville, Virginia, 22908, United States
Virginia Commonwealth University

Richmond, Virginia, 23298, United States

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