One-person trial aims to curb obesity in rare genetic condition
NCT ID NCT07496463
First seen Apr 06, 2026 · Last updated May 16, 2026 · Updated 3 times
Summary
This study tests a drug called setmelanotide in one person with pseudohypoparathyroidism type 1a (PHP1a), a rare genetic disorder that often causes severe obesity. The goal is to see if the drug can lead to at least 5% weight loss over 6 months. The participant must have a confirmed GNAS mutation and stable treatment for diabetes and high cholesterol.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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