Higher antidepressant dose may pose greater risk for seniors with kidney issues
NCT ID NCT07387120
Summary
This study looked at whether starting older adults with reduced kidney function on a higher dose (50mg) of the antidepressant sertraline is riskier than starting on a lower dose (25mg). Researchers analyzed health records from over 6,800 adults aged 66+ in Canada who were newly prescribed the medication. They compared the 30-day risk of serious events like hospitalization, emergency room visits, or death between the two dose groups.
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Contacts and locations
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Locations
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London Health Sciences Centre Research Institute
London, Ontario, Canada
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