New combo aims to wipe out breast cancer before surgery

NCT ID NCT07466303

First seen Mar 13, 2026 · Last updated May 14, 2026 · Updated 11 times

Summary

This study tests whether giving two drugs—Serplulimab and trastuzumab rezetecan—before surgery can eliminate all signs of triple-negative breast cancer in 84 women. The goal is to see if this approach leads to a complete response (no cancer left in the breast or lymph nodes). Participants will receive the combination as neoadjuvant therapy, then have surgery to check results.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • the First Affiliated Hospital of the Air Force Medical University

    Xi'an, 710032, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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