New combo therapy aims to tame ulcerative colitis faster and safer

NCT ID NCT06095596

First seen May 03, 2026 · Last updated May 13, 2026 · Updated 2 times

Summary

This study tests a new way to treat moderate to severe ulcerative colitis by using two drugs in sequence. First, a fast-acting drug (upadacitinib) is given for 8 weeks to quickly bring the disease under control, then patients switch to a safer long-term drug (vedolizumab) to keep symptoms away. The goal is to see if this approach works better than standard treatments. About 334 adults with active ulcerative colitis will take part.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ULCERATIVE COLITIS (UC) are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • the Sixth Affiliated Hospital of Sun Yat-Sen University

    RECRUITING

    Guangzhou, Guangdong, 501655, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.