Tiny particles in the blood may hold clues to sepsis severity
NCT ID NCT07727265
First seen Jul 27, 2026 · Last updated Jul 28, 2026 · Updated 1 time
Summary
This study looks at whether small particles released by dying cells, called PyroEVs, and a protein called PLIN3 are linked to how severe sepsis is and how well patients recover. Researchers will measure these in the blood of 180 people with sepsis and compare them to healthy volunteers. The goal is to see if these markers can help predict 28-day survival and organ failure.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If PyroEVs and PLIN3 prove to be reliable markers, they could help doctors better predict sepsis outcomes and guide treatment decisions.
- What could go wrong
- This is an observational study, not a treatment trial. It may find no clear link, and the results may not apply to all sepsis patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Zhongda Hospital, Southeast University
RECRUITINGNanjing, Jiangsu, 210009, China
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Other studies related to the condition(s) this trial covers.
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