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Blood gas clues could reveal hidden danger in sepsis patients

NCT ID NCT07711405

Knowledge-focused Sponsor: Gaziosmanpasa Research and Education Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 17, 2026 · Last updated Jul 17, 2026

Summary

This study looks at whether measuring oxygen and carbon dioxide differences in the blood can help predict which sepsis patients in the ICU are at highest risk of dying within 28 days. Researchers will track these levels in 88 intubated patients with sepsis who have a central venous catheter. The goal is to see if these simple blood gas readings can give early warning of organ failure and poor outcomes.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could give doctors a simple, bedside tool to better predict which sepsis patients are at highest risk of dying, allowing earlier and more targeted treatment.
What could go wrong
This is a small, observational study, not a treatment trial. The findings may not apply to all sepsis patients, and the measurements may not reliably predict outcomes in routine practice.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

88 people

The number who actually took part.

Started

Mar 2025

Finished

Jan 2026

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

İntubated icu patients who diagnosed with sepsis

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adult patients aged 18 years or older * Diagnosis of sepsis * Admission to the intensive care unit * Intubated and receiving invasive mechanical ventilation * Presence of a central venous catheter Exclusion Criteria: * Patients younger than 18 years * Patients in whom a central venous catheter cannot be placed * Patients receiving oxygen therapy via face mask or nasal cannula * Patients treated with non-invasive mechanical ventilation

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Conditions

The condition(s) this trial relates to.

infectious disease with sepsis Sepsis toxic shock syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Intubated icu patients Sepsis and septic shock

Contacts and locations

Locations

  • Gaziosmanpasa Training and Research Hospital

    Istanbul, Gaziosmanpasa, 34255, Turkey (Türkiye)

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