Can big data defeat the ICU's deadliest foe?
NCT ID NCT07770347
First seen Aug 18, 2026 · Last updated Aug 19, 2026 · Updated 1 time
Summary
This study follows thousands of critically ill patients in intensive care units across China to better understand sepsis, a life-threatening condition where the body's response to infection damages its own organs. Researchers will collect detailed information on infections, treatments, and patient outcomes to identify risk factors and develop tools for earlier detection and more personalized care. The goal is to reduce the high death rate and improve recovery for sepsis patients.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Individualized anti-infective therapy (antibiotics, antifungals) and immunomodulatory therapy (corticosteroids, immunoglobulins) as prescribed by the attending physician.
- What this could lead to
- If successful, this could lead to better early warning systems, more accurate diagnosis, and personalized treatment strategies for sepsis, potentially reducing its high death rate in ICUs.
- What could go wrong
- This is an observational study, not a controlled trial, so it cannot prove that any specific treatment works. The findings may not apply to other countries or healthcare settings.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 2,400 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jun 2026
- Expected to finish
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Jun 2031
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age ≥ 18 years * ICU stay ≥ 24 hours * Informed consent signed by the patient or their legal representative Exclusion Criteria: * ICU stay \< 24 hours * Refusal to provide informed consent * Pregnancy or lactation * Receiving palliative care or expected survival \< 24 hours * Previously enrolled in this study * Severe immunodeficiency (HIV infection, or long-term use of corticosteroids/immunosuppressants)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Beijing Chao Yang Hospital
Beijing, Beijing Municipality, 100020, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Persistent inflammation, immunosuppression and catabolism syndrome (PICS): a new horizon for surgical critical care subtitle: cardiac dysfunction in older sepsis survivors subtitle: development of a designer Proline-Rich antimicrobial peptide chaperone protein inhibitor (DPC) for treating sepsis
- A randomized clinical trial of early empiric Anti-Mycobacterium tuberculosis therapy for sepsis in Sub-Saharan africa
- Tracing of real-time glu13Cose metabolism in human immune cells - intensive care unit
- Could a neck vein check replace a harder ultrasound for ICU fluid management?
- Sepsis alert system aims to speed up critical care response in hospitals
- Can tracking ambulance ventilators improve emergency breathing care?