New hospital risk scores aim to spot sepsis and sudden deterioration earlier

NCT ID NCT06779617

First seen Oct 31, 2025 · Last updated Jun 19, 2026 · Updated 38 times

Summary

This study is testing two new risk scores that predict a patient's chance of developing sepsis or experiencing a sudden decline (like cardiac arrest or death) within the next 4 hours. The scores give a simple 1-to-4 color-coded risk level to alert hospital staff. The goal is to see if providing these scores helps doctors and nurses check on high-risk patients sooner. The trial will involve about 150,000 adult patients across multiple hospitals in the University of Maryland Medical System.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Maryland Baltimore Washington Medical Center

    NOT_YET_RECRUITING

    Glen Burnie, Maryland, 21061, United States

  • University of Maryland Capital Region Medical Center

    RECRUITING

    Largo, Maryland, 20774, United States

  • University of Maryland Charles Regional Medical Center

    NOT_YET_RECRUITING

    La Plata, Maryland, 20646, United States

  • University of Maryland Medical Center

    NOT_YET_RECRUITING

    Baltimore, Maryland, 21201, United States

  • University of Maryland Medical Center - Midtown

    RECRUITING

    Baltimore, Maryland, 21201, United States

  • University of Maryland Shore Medical Center

    NOT_YET_RECRUITING

    Easton, Maryland, 21601, United States

  • University of Maryland St. Joseph Medical Center

    NOT_YET_RECRUITING

    Towson, Maryland, 21204, United States

  • University of Maryland Upper Chesapeake Medical Center

    NOT_YET_RECRUITING

    Bel Air, Maryland, 21014, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

clinical decision support tool (SEPSys Score and RESCUE Score)

What this could lead to

If successful, this could help hospitals identify patients at risk of sepsis or sudden decline earlier, potentially saving lives.

What could go wrong

This is a large pragmatic trial testing a prediction tool, not a treatment. The scores may not improve outcomes or could lead to unnecessary alarms.

Conditions

The condition(s) this trial relates to.

infectious disease with sepsis Sepsis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.