New hospital risk scores aim to spot sepsis and sudden deterioration earlier

NCT ID NCT06779617

Recruiting now Knowledge-focused Sponsor: University of Maryland, Baltimore Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing two new risk scores that predict a patient's chance of developing sepsis or experiencing a sudden decline (like cardiac arrest or death) within the next 4 hours. The scores give a simple 1-to-4 color-coded risk level to alert hospital staff. The goal is to see if providing these scores helps doctors and nurses check on high-risk patients sooner. The trial will involve about 150,000 adult patients across multiple hospitals in the University of Maryland Medical System.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: clinical decision support tool (SEPSys Score and RESCUE Score)
What this could lead to: If successful, this could help hospitals identify patients at risk of sepsis or sudden decline earlier, potentially saving lives.
What could go wrong: This is a large pragmatic trial testing a prediction tool, not a treatment. The scores may not improve outcomes or could lead to unnecessary alarms.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

infectious disease with sepsis Sepsis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PATIENT DETERIORATION SEPSIS

Contacts and locations

Locations

University of Maryland Baltimore Washington Medical Center
NOT_YET_RECRUITING

Glen Burnie, Maryland, 21061, United States
University of Maryland Capital Region Medical Center
RECRUITING

Largo, Maryland, 20774, United States
University of Maryland Charles Regional Medical Center
NOT_YET_RECRUITING

La Plata, Maryland, 20646, United States
University of Maryland Medical Center
NOT_YET_RECRUITING

Baltimore, Maryland, 21201, United States
University of Maryland Medical Center - Midtown
RECRUITING

Baltimore, Maryland, 21201, United States
University of Maryland Shore Medical Center
NOT_YET_RECRUITING

Easton, Maryland, 21601, United States
University of Maryland St. Joseph Medical Center
NOT_YET_RECRUITING

Towson, Maryland, 21204, United States
University of Maryland Upper Chesapeake Medical Center
NOT_YET_RECRUITING

Bel Air, Maryland, 21014, United States

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