Could a steroid cocktail save more sepsis patients? major trial launches
NCT ID NCT04280497
First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 31 times
Summary
This study tests whether adding two steroids (hydrocortisone and fludrocortisone) to standard care can reduce death or long-term organ failure in adults with sepsis. About 1,800 ICU patients will be randomly assigned to receive the steroid combination or a placebo. The main goal is to see if the treatment improves survival and helps patients recover without needing machines to breathe or support their kidneys or blood pressure.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Department of medical and surgical Intensive Care Unit, Raymond Poincaré Hospital - APHP
RECRUITINGGarches, Hauts-de-Seine, 92380, France
Conditions
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