Could a steroid combo be the key to fighting sepsis? major trial launches

NCT ID NCT04280497

First seen Nov 01, 2025 · Last updated Apr 28, 2026 · Updated 26 times

Summary

This study aims to find out which sepsis patients benefit most from a combination of two steroids (hydrocortisone and fludrocortisone). About 1,800 adults in intensive care will receive either the steroid combo or a placebo. The main goal is to see if the treatment reduces death or the need for machines to help with breathing, kidney function, or blood pressure at 90 days.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for SEPSIS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Department of medical and surgical Intensive Care Unit, Raymond Poincaré Hospital - APHP

    RECRUITING

    Garches, Hauts-de-Seine, 92380, France

Conditions

Explore the condition pages connected to this study.