New drug aims to tame deadly blood clots in sepsis patients

NCT ID NCT06854640

Recruiting now Disease control Sponsor: Bayer Source: ClinicalTrials.gov ↗

First seen Apr 03, 2026 · Last updated Apr 30, 2026 · Updated 3 times

Summary

This early-stage study tests a new medicine called BAY 3389934 in 36 adults with sepsis-induced coagulopathy, a condition where the body's response to infection causes dangerous blood clots. Participants are in the ICU and receive the drug through an IV. The main goal is to check safety and find the right dose. The study lasts about 28 days and involves blood tests, physical exams, and heart monitoring.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

CHRU de Tours - Hôpital Bretonneau - Médecine Intensive Réanimation
NOT_YET_RECRUITING

Tours, Centre-Val de Loire, 37044, France
Canisius WIlhelmina Ziekenhuis - Intensive Care
NOT_YET_RECRUITING

Nijmegen, Gelderland, 6532 SZ, Netherlands
Centre Hospitalier Départemental Vendée - Service de réanimation polyvalente
NOT_YET_RECRUITING

La Roche-sur-Yon, Pays de la Loire Region, 85000, France
Centre Hospitalier Universitaire (CHU) de Liege - Domaine Universitaire du Sart Tilman - Intensive Care
NOT_YET_RECRUITING

Liège, 4000, Belgium
Centre Hospitalier Universitaire d'Angers - Médecine Intensive Réanimation et Médecine Hyperbare
NOT_YET_RECRUITING

Angers, Pays de la Loire Region, 49100, France
Centre Hospitalier Universitaire de Limoges Dupuytren 1 - Service de réanimation polyvalente
NOT_YET_RECRUITING

Limoges, New Aquitaine, 87042, France
Clinique Saint-Pierre d'Ottignies - Intensive Care
RECRUITING

Ottignies-Louvain-la-Neuve, 1340, Belgium
Erasmus Medisch Centrum - Intensive Care
NOT_YET_RECRUITING

Rotterdam, South Holland, 3015 GD, Netherlands
Hopital Hotel Dieu Nantes - Service de Médecine Intensive Réanimation
NOT_YET_RECRUITING

Nantes, Pays de la Loire Region, 44000, France
Hopitaux Universitaires de Strasbourg Nouvel Hopital Civil - Service de Médecine Intensive Réanimation
RECRUITING

Strasbourg, Grand Est, 67091, France
Hôpital Raymond-Poincaré - Service de Médecine Intensive - Réanimation, Médecine Hyperbare
NOT_YET_RECRUITING

Garches, Île-de-France Region, 92380, France
Jeroen Bosch Ziekenhuis - Intensive Care
NOT_YET_RECRUITING

's-Hertogenbosch, North Brabant, 5223 GZ, Netherlands
Kliniken der Stadt Köln gGmbH - Krankenhaus Merheim - Lungenklinik
NOT_YET_RECRUITING

Cologne, North Rhine-Westphalia, 51109, Germany
Klinikum der Universität München AöR - Klinik für Anaesthesiologie (Campus Großhadern)
NOT_YET_RECRUITING

München, 81377, Germany
Medisch Spectrum Twente - Intensive Care
NOT_YET_RECRUITING

Enschede, Overijssel, 7512 KZ, Netherlands
UZ Antwerpen - Intensive Care
NOT_YET_RECRUITING

Edegem, 2650, Belgium
Universitaetsklinikum Carl Gustav Carus an der Technischen Universitaet Dresden | Medizinische Klinik I - FB Haemostaseologie
NOT_YET_RECRUITING

Dresden, 01307, Germany
Universitair Medisch Centrum St. Radboud - Intensive Care
NOT_YET_RECRUITING

Nijmegen, Gelderland, 6525 GA, Netherlands
Universite Catholique de Louvain (UCL) - Cliniques Universitaires Saint-Luc - Intensive Care
NOT_YET_RECRUITING

Woluwe-Saint-Lambert, 1200, Belgium
Universitätsklinikum Leipzig AöR | Interdisziplinare Internistische Intensivmedizin
NOT_YET_RECRUITING

Leipzig, 04103, Germany

Conditions

Explore the condition pages connected to this study.

COAGULOPATHY COAGULOPATHY SEPSIS