New blood filter for sepsis: does it remove Life-Saving antibiotics?

NCT ID NCT06602245

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether a blood-filtering device called Efferon LPS removes antibiotics from the blood of people with sepsis. Sepsis is a severe infection that can lead to organ failure, and doctors sometimes use filters to clean the blood. The study included 30 patients and measured how much antibiotic was cleared by the filter. The goal was to see if the filter might accidentally reduce antibiotic levels, which could make treatment less effective.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Efferon LPS hemoperfusion device

What this could lead to

If successful, this could help doctors understand how to safely use the Efferon LPS device without reducing antibiotic effectiveness in sepsis patients.

What could go wrong

This is a small pilot study with only 30 participants, so results may not apply to all patients. It only measures drug clearance, not patient outcomes.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

infectious disease with sepsis Sepsis toxic shock syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • N. V. Sklifosovsky Moscow Research Institute of Emergency

    Moscow, Russia

  • N.I. Pirogov City Clinical Hospital No. 1

    Moscow, Russia

  • Nizhny Novgorod Regional Clinical Hospital named after N.A. Semashko

    Nizhny Novgorod, Russia

  • Perm regional clinical hospital

    Perm, Russia