Weekly shot shows promise in reversing prediabetes and cutting weight

NCT ID NCT05040971

Summary

This study tested whether a weekly injection called semaglutide could help people with obesity and prediabetes lose weight and return their blood sugar to normal levels. Over 200 participants received either the real medicine or a placebo dummy injection for one year, alongside lifestyle advice. The main goals were to see how much weight people lost and whether their prediabetes improved.

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Contacts and locations

Locations

  • Aarhus Universitetshospital Diabetes og Hormonsygdomme

    Aarhus N, 8200, Denmark

  • C-endo Diab Endo Clin Calgery

    Calgary, Alberta, T2V 4J2, Canada

  • CHU de Quebec-Universite Laval

    Québec, G1V 4G2, Canada

  • Centre Medical Acadie

    Montreal, Quebec, H4N 2W2, Canada

  • Centre de recherché du CHUS

    Sherbrooke, Quebec, J1H 5N4, Canada

  • Centricity Research LMC

    Toronto, Ontario, M4G 3E8, Canada

  • Claremont Medical Practice

    Exmouth, EX8 2JF, United Kingdom

  • Clifton Medical Centre

    Rotherham, South Yorkshire, S65 1DA, United Kingdom

  • Clinique Medicine Urbaine du Quartier Latin, Inc.

    Montreal, Quebec, QC H2L 4E9, Canada

  • Ctr de Med Metab de Lanaudiere

    Terrebonne, Quebec, J6X 4P7, Canada

  • Diabetes Heart Research Centre

    Toronto, Ontario, M6G 1M2, Canada

  • Dr Anil K Gupta Med Prof Corp

    Toronto, Ontario, M9V 4B4, Canada

  • G.A. Research Associates Ltd.

    Moncton, New Brunswick, E1G 1A7, Canada

  • GP Direct

    Harrow, HA2 0RQ, United Kingdom

  • Guys Hospital

    London, SE1 9RT, United Kingdom

  • Hospital Clinico San Carlos

    Madrid, 28040, Spain

  • Hospital Gregorio Marañón

    Madrid, 28009, Spain

  • Hospital Infanta Luisa

    Seville, 41010, Spain

  • Hvidovre Hospital Endokrinologisk forsknings afsnit 159

    Hvidovre, 2650, Denmark

  • Institut universitaire de cardiologie

    Québec, G1V 4G5, Canada

  • LMC Clin Res Inc. Calgary

    Calgary, Alberta, T2H 2G4, Canada

  • LMC Clin Res Inc. Thornhill

    Concord, Ontario, L4K 4M2, Canada

  • LMC Clin Rsrch Inc. (Montreal)

    Saint-Laurent, Quebec, H4T 1Z9, Canada

  • LMC ClinRsrh Inc.Brampton

    Brampton, Ontario, L6S 0C6, Canada

  • LMC Clinical Research Inc. Oakville

    Oakville, Ontario, L6M 1M1, Canada

  • LMC Diabetes & Endocrinology (Barrie)

    Barrie, Ontario, L4N 7L3, Canada

  • LMC Endo Ctr (Etobicoke) Ltd

    Etobicoke, Ontario, M9R 4E1, Canada

  • LMC Research Inc. Ottawa

    Nepean, Ontario, K2J 0V2, Canada

  • Manna Research Mirabel

    Mirabel, Quebec, J7J 2K8, Canada

  • Milestone Research

    London, Ontario, N5W 6A2, Canada

  • MyHealth - Strensall Health Care Centre

    Strensall, YO32 5UA, United Kingdom

  • Nova Scotia Hlth Halifax

    Halifax, Nova Scotia, B3H 2Y9, Canada

  • Obesity Research Unit

    Helsinki, 00014, Finland

  • Ocean West Research Clinic

    Surrey, British Columbia, V3Z 2N6, Canada

  • Premier Clinical Trial Research Network (PCTRN)

    Hamilton, Ontario, L8M 1K7, Canada

  • StudyCor

    Jyväskylä, 40620, Finland

  • The Health Centre

    Bradford-on-Avon, BA15 1DQ, United Kingdom

  • The Staploe Medical Centre

    Soham, CB7 5JD, United Kingdom

  • Toronto Sleep Institute/MedSleep

    Toronto, Ontario, M4P 1P2, Canada

  • University Hospital Coventry - WISDEM Centre

    Coventry, CV2 2DX, United Kingdom

  • University of Calgary

    Calgary, Alberta, T2T 5C7, Canada

  • Weight Wise Clinic

    Edmonton, Alberta, T6G 2R3, Canada

  • Wharton Med Clin Trials

    Hamilton, Ontario, L8L 5G8, Canada

Conditions

Explore the condition pages connected to this study.