Could a diabetes drug protect kidneys in type 1 diabetes?

NCT ID NCT05822609

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing whether semaglutide, a drug already used for type 2 diabetes, can reduce kidney damage in people with type 1 diabetes and diabetic kidney disease. About 60 adults will receive either semaglutide or a placebo for 26 weeks. Researchers will measure changes in urine protein levels and kidney function to see if the drug helps protect the kidneys.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

semaglutide

What this could lead to

If it works, this could point toward a new treatment to slow kidney damage in people with type 1 diabetes.

What could go wrong

This is a small, early-phase trial with only 60 participants, so results may not apply to everyone. Semaglutide can cause side effects like nausea and vomiting, and its safety in type 1 diabetes is not fully known.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for TYPE 1 DIABETES are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

diabetic kidney disease type 1 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Providence Sacred Heart Medical Center

    RECRUITING

    Spokane, Washington, 99204, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Toronto General Hospital, University Health Network

    RECRUITING

    Toronto, Ontario, M5G2N2, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Colorado Anschutz Medical Campus

    RECRUITING

    Aurora, Colorado, 80045, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Washington

    RECRUITING

    Seattle, Washington, 98104, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••