Could a diabetes drug sharpen your mind? new study explores

NCT ID NCT04466345

First seen Nov 01, 2025 · Last updated May 13, 2026 · Updated 31 times

Summary

This study looked at whether semaglutide, a drug used for diabetes and weight loss, can help improve thinking and memory problems in people with major depression. The trial included 72 overweight adults aged 18 to 60 who had below-average scores on a thinking test. Participants received either semaglutide or a placebo, and researchers measured changes in executive function, like focus and mental flexibility.

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Contacts and locations

Locations

  • Toronto Western Hospital

    Toronto, Ontario, M5T 2S8, Canada

Conditions

Explore the condition pages connected to this study.