New combo therapy offers hope for myeloma patients who stop responding to treatment

NCT ID NCT04661137

First seen Feb 11, 2026 · Last updated May 14, 2026 · Updated 12 times

Summary

This study tests whether adding the drug selinexor to standard treatments (carfilzomib, daratumumab, or pomalidomide) can help people with multiple myeloma whose cancer has worsened on their current therapy. About 96 adults will receive the combination until their disease progresses or side effects become unmanageable. The main goal is to see how many patients achieve a partial or complete response.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • John Theurer Cancer Center

    Hackensack, New Jersey, 07601, United States

  • Lombardi Comprehensive Cancer Center

    Washington D.C., District of Columbia, 20007, United States

Conditions

Explore the condition pages connected to this study.