New hope for kids with tough leukemia: drug combo targets rare gene

NCT ID NCT07437170

First seen Feb 28, 2026 · Last updated May 16, 2026 · Updated 10 times

Summary

This study tests whether adding the drug selinexor to standard chemotherapy can help children with a rare, high-risk form of acute myeloid leukemia (AML) caused by a NUP98 gene change. Ten children will receive the combination during their first two rounds of chemo. The goal is to see if more children achieve complete remission and have better long-term survival.

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Contacts and locations

Locations

  • Children's Hospital, Zhejiang University School of Medicine

    Hangzhou, Zhejiang, 310000, China

Conditions

Explore the condition pages connected to this study.