Home exercise program aims to keep stroke survivors active and cut heart risk

NCT ID NCT07799987

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
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Status unknown
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First seen Sep 02, 2026 · Last updated Sep 03, 2026 · Updated 1 time

Summary

This pilot study tests whether stroke survivors can follow a self-managed exercise program at home to maintain their health. Participants first complete an 18-session guided program with respiratory, strengthening, and cardiovascular exercises, plus weekly virtual coaching sessions. After that, they try to continue exercising on their own for two months, aiming for 150 minutes of moderate to vigorous activity per week. The goal is to see if this approach is feasible and helps reduce the risk of secondary stroke and heart problems.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
A home-based exercise program combining respiratory muscle training, strengthening exercises, and cardiovascular exercise, plus a behavioral management program with motivational interviewing and goal setting.
What this could lead to
If it works, this could point toward a practical way for stroke survivors to stay active long-term, potentially lowering their risk of another stroke and heart problems.
What could go wrong
This is a small pilot study with only 23 participants, so results may not apply to everyone. It tests feasibility, not effectiveness, and some people may find it hard to stick with the exercise routine.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 23 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2026

An estimate. Start dates often move.

Expected to finish

May 2029

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 89 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. -diagnosis of stroke \> six months \< 10 years since stroke onset, 2. \> 18 years; \<90 of age, 3. Montreal Cognitive Assessment - BLIND score \> 19, 4. able to stand from chair and remain standing independently, 5. able to walk 20 feet without physical assistance, 6. no other neurological diagnosis, 7. no history of intermittent claudication, 8. no angina at rest or with minimal exertion, 9. no history of chronic obstructive pulmonary disease, 10. not currently receiving physical rehabilitation services, 11. ability to express pain, fatigue or the need for assistance, 12. ability to follow a three-step command or mimic exercises 13. approval from primary care physician to participate Exclusion Criteria: 1. a neurologic condition other than stroke, i.e. Parkinson's Disease, multiple sclerosis, 2. severe, functional limiting arthritis, 3. orthopedic condition that limits mobility, 4. severe weight-bearing pain, 5. current participation in other physical rehabilitation services or exercise programs, 6. Serious cardiac conditions (hospitalization for myocardial infarction or heart surgery within the past year, history of congestive heart failure, documented serious and unstable cardiac arrhythmias, hypertrophic cardiomyopathy, severe aortic stenosis, angina or dyspnea at rest or during activities of daily living). Anyone meeting New York Heart Association criteria for Class 3 or Class 4 heart disease will be excluded, 7. Severe hypertension: with systolic \> 200 mmHg and diastolic \> 110 mmHg at rest, that cannot be medically controlled into the resting range of 180/100 mmHg, 8. use of supplemental oxygen at baseline, 9. severe obstructive pulmonary disease (Classification of Global Initiative for Chronic Obstructive Lung Disease (GOLD) 3 or higher, indicating FEV1\<50% predicted), 10. treatment for pneumonia or lower respiratory infection within the past month, 11. able to run one-quarter mile without stopping; 12. women who are pregnant

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Conditions

The condition(s) this trial relates to.

Motor Activity stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Malcom Randall VAMC

    Gainesville, Florida, 32608, United States

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