Could a new dose help kids with rare lung disease?

NCT ID NCT03492177

Ongoing Disease control Sponsor: Actelion Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 17, 2026 · Updated 34 times

Summary

This study tests the right dose of selexipag for children aged 2 to 18 with pulmonary arterial hypertension (PAH), a serious lung condition that makes it hard for the heart to pump blood. Researchers want to make sure the drug levels in children are similar to those in adults. The study involves 63 children and focuses on safety and how the body processes the medication.

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Contacts and locations

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Locations

Almazov National Medical Research Center Of The Ministry Of Health Of The Russian Federation

Saint Petersburg, 197341, Russia
Beijing Anzhen Hospital

Beijing, 100029, China
CHU Arnaud de Villeneuve

Montpellier, 34295, France
Centre Hospitalier Sainte Justine

Montreal, Quebec, H3T 1C4, Canada
Children'S Hospital Cardiac Care Center University Of Colorado

Aurora, Colorado, 80045, United States
Chu Hopital Des Enfants

Toulouse, 31059, France
Gottsegen Gyorgy Orszagos Kardiologiai Intezet, Felnott kardiologiai osztaly

Budapest, 1096, Hungary
Great Ormond Street Hospital

London, WC1N 3JH, United Kingdom
Health Institution 4Th City Children'S Clinical Hospital

Minsk, 220118, Belarus
Hôpital Necker - Enfants Malades

Paris, 75015, France
Institut Jantung Negara (National Heart Institute)

Kuala Lumpur, 50400, Malaysia
Institut Za Zdravstvenu Zastitu Majke I Deteta Srbije Dr Vukan Cupic

Belgrade, 11070, Serbia
Kazan State Medical University

Kazan', 420059, Russia
Lviv Regional Clinical Hospital

Lviv, 79010, Ukraine
Moscow Scientific Research Institute For Pediatrics And Childrens Surgery Of Rosmedtechnologies

Moscow, 125412, Russia
Municipal Enterprise Of The Dnipropetrovsk Regional Council

Dnipro, 49070, Ukraine
Municipal Institution Of The Zaporizhzhya Regional Council

Zaporizhzhya, 69063, Ukraine
National Cheng Kung University Hospital

Tainan, 704, Taiwan
National Taiwan University Hospital

Taipei, 100, Taiwan
Saint Petersburg State Pediatric Medical University

Saint Petersburg, 194100, Russia
Samara Regional Clinical Cardiological Dispensary

Samara, 443070, Russia
Sarawak Heart Center

Kota Samarahan, 94300, Malaysia
Schneider Children's Medical Center

Petach Tikvah, Israel
Scientific and Research Institution of Cardiovascular Diseases Complex Problems

Kemerovo, 650002, Russia
Seattle Children's Hospital

Seattle, Washington, 98105, United States
Shanghai Childrens Medical Center

Shanghai, 200127, China
Sheba Medical Center

Ramat Gan, 52621, Israel
State Institution Of The Ministry Of Health Of Ukraine

Kiev, 04050, Ukraine
State Institution Republican Scientific And Practical Center For Pediatric Surgery

Minsk, 220013, Belarus
UZ Gent

Ghent, 9000, Belgium
University of Iowa Hospital

Iowa City, Iowa, 52242, United States
Universitätsklinikum Freiburg Zentrum

Freiburg im Breisgau, 70106, Germany
Univerzitetska Dečja Klinika

Belgrade, 11000, Serbia
Wojewodzki Szpital Specjalistyczny We Wroclawiu

Wroclaw, 51 124, Poland

Conditions

Explore the condition pages connected to this study.

PULMONARY ARTERIAL HYPERTENSION