Heart valve study: is being awake or asleep better during procedure?

NCT ID NCT04347603

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at 218 people with severe aortic stenosis (a narrowed heart valve) who needed a procedure called TAVI to replace the valve without open-heart surgery. Researchers compared two approaches: general anesthesia (being fully asleep) versus local anesthesia with sedation (being awake but relaxed). The goal was to see if general anesthesia was as safe and effective as the lighter sedation method, focusing on complications and recovery within the first 72 hours.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University hospital

    Montpellier, France

  • University hospital

    Nîmes, France