New sedation strategy aims to cut delirium in ventilated kids

NCT ID NCT04801589

First seen Nov 01, 2025 · Last updated Apr 24, 2026 · Updated 25 times

Summary

This study compares two sedative medications—dexmedetomidine and midazolam—in children aged 44 weeks to 11 years who are on breathing machines in the ICU. The goal is to see which drug reduces delirium (a form of temporary brain dysfunction) and improves recovery, including time on the ventilator and long-term thinking and behavior. About 372 children will participate, and results may help set a new standard for safer sedation in pediatric intensive care.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Vanderbilt University Medical Center

    RECRUITING

    Nashville, Tennessee, 37232, United States

    Contact

Conditions

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