Could a gentler cleaning method make cavity sealants last longer?
NCT ID NCT07725133
First seen Jul 24, 2026 · Last updated Jul 24, 2026
Summary
This trial tests whether cleaning the chewing surfaces of children's teeth with a fine erythritol powder spray (Guided Biofilm Therapy) before applying a protective sealant helps the sealant stay in place longer than the standard rotary-brush polishing. Each child aged 6–10 will receive both methods on opposite sides of the mouth, and the sealants will be checked over three years. The goal is to see which cleaning approach leads to better sealant retention and fewer cavities.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Guided Biofilm Therapy with erythritol powder vs. conventional rotary-brush polishing, both followed by resin-based pit and fissure sealant
- What this could lead to
- If one cleaning method proves better, it could improve how long dental sealants last, offering better cavity prevention for children.
- What could go wrong
- This is a small, early-stage trial in one university. Results may not apply to all children or dental settings, and both methods already have some evidence behind them.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Marmara University
Istanbul, Maltepe, 34384, Turkey (Türkiye)
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