Baby eczema cream may stop food allergies before they start

NCT ID NCT03742414

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether using a special skin barrier cream (Epiceram) twice a day, along with a steroid cream at the first sign of eczema, can prevent food allergies in babies who develop eczema by 12 weeks old. The goal is to see if this proactive skin care reduces the number of foods the babies become allergic to. The trial enrolled 398 infants and is currently active but no longer recruiting.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Tri-lipid skin barrier cream (Epiceram) and fluticasone propionate cream

What this could lead to

If it works, this could point toward a simple skin care routine that prevents food allergies in babies with eczema.

What could go wrong

This is a Phase 2 trial, so results are still early. The approach may not prevent allergies for all babies, and steroid creams have potential side effects with long-term use.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

atopic eczema dermatitis Eczema food allergy prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Cincinnati Children's Hospital Medical Center

    Cincinnati, Ohio, 45229, United States

  • Division of Pediatric Allergy and Clinical Immunology, National Jewish Health

    Denver, Colorado, 80206, United States

  • Sean N. Parker Center for Allergy & Asthma Research at Stanford University

    Palo Alto, California, 94304, United States

  • University of Chicago

    Chicago, Illinois, 60637, United States

  • • King's College London and Guy's and St. Thomas' NHS Foundation Trust, UK

    London, London, United Kingdom