New vaccine combo shows promise in advanced skin cancer trial
NCT ID NCT04079166
First seen Dec 30, 2025 · Last updated Jun 14, 2026 · Updated 32 times
Summary
This study tests two experimental cancer vaccines, SCIB1 and iSCIB1+, given alongside standard immunotherapy drugs (nivolumab with ipilimumab or pembrolizumab) for people with advanced melanoma that cannot be removed by surgery. The goal is to see if adding the vaccines is safe and can improve how well the standard treatments work. About 173 participants will take part in this phase 2 trial.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Cambridge University Hospitals NHS Foundation Trust
Cambridge, United Kingdom
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East and North Hertfordshire NHS Trust
Northwood, United Kingdom
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Guy's & St Thomas' NHS Foundation Trust
London, United Kingdom
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Lancashire Teaching Hospitals NHS Foundation Trust
Preston, United Kingdom
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Nottingham University Hospitals NHS Trust
Nottingham, United Kingdom
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Oxford University Hospital NHS Foundation Trust
Oxford, United Kingdom
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Royal Free London NHS Foundation Trust
London, United Kingdom
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Sheffield Teaching Hospital NHS Foundation Trust
Sheffield, United Kingdom
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Somerset NHS Foundation Trust
Taunton, United Kingdom
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The Christie NHS Foundation Trust
Manchester, United Kingdom
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The Leeds Teaching Hospitals NHS Trust
Leeds, United Kingdom
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The Royal Marsden NHS Foundation Trust
London, United Kingdom
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University Hospital Plymouth NHS Trust
Plymouth, United Kingdom
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University Hospital Southampton NHS Foundation Trust
Southampton, United Kingdom
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Velindre University NHS Trust
Cardiff, United Kingdom
Conditions
Explore the condition pages connected to this study.