Zapping the heart: could radiation tame dangerous rhythms?

NCT ID NCT04843683

Recruiting now Disease control Sponsor: University Health Network, Toronto Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a single, precise dose of radiation to the heart to treat dangerous arrhythmias in 60 patients who haven't improved with medication or standard procedures. Researchers will monitor changes in heart rhythm events and medication use over 18 months. The goal is to see if this non-invasive approach can safely control the condition.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Stereotactic ablative radiotherapy (SBRT)
What this could lead to: If it works, this could offer a non-invasive option to control heart arrhythmias without surgery or long-term medication.
What could go wrong: This is a small, early-phase trial with only 60 participants. It may not work for everyone, and radiation to the heart carries risks like damage to nearby tissues.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Arrhythmias, Cardiac ventricular arrhythmias due to cardiac ryanodine receptor calcium release deficiency syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CARDIAC ARRHYTHMIA

Contacts and locations

Locations

Princess Margaret Cancer Center, University Health Network
RECRUITING

Toronto, Ontario, M5G 2M9, Canada

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