Radiation instead of surgery? new trial for elderly breast cancer patients

NCT ID NCT06523894

Recruiting now Disease control Sponsor: University Hospital, Geneva Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a precise, high-dose radiation technique called SBRT as an alternative to surgery for breast cancer in patients over 70 who are too frail for an operation. The goal is to find the safest highest dose that can be given in one to five sessions. If it works, it could offer a less invasive option for those who cannot have surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Stereotactic body radiotherapy (SBRT) – high-precision radiation
What this could lead to: If successful, this could offer a non-surgical treatment option for elderly or frail breast cancer patients who cannot undergo surgery.
What could go wrong: This is an early-phase trial with only 36 participants, so it is too small to prove effectiveness. The main goal is to find a safe dose, not to confirm that the treatment works.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BREAST CANCER

Contacts and locations

Locations

Radiation Oncology Department, Geneva University Hospital
RECRUITING

Geneva, 1205, Switzerland

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