New hope for hard-to-treat lung cancer: drug duo outperforms chemo in late-stage trial

NCT ID NCT05015608

First seen Jun 05, 2026 · Last updated Jun 13, 2026 · Updated 2 times

Summary

This study tested whether a combination of two targeted drugs (savolitinib and osimertinib) works better than standard chemotherapy for people with advanced non-small cell lung cancer that has a specific genetic change (MET amplification) and has stopped responding to first-line treatment. 216 adults took part. The goal was to see if the drug combo could delay cancer growth and how safe it was. This is a disease control study, not a cure, as ongoing treatment is needed.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Shanghai Chest Hospital

    Shanghai, Shanghai Municipality, 210000, China

Conditions

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Conditions inferred from the trial description

These were inferred from the trial's summary, not listed by the trial registrant.