Could a quicker dose Ramp-Up make CLL treatment easier?

NCT ID NCT04843904

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests whether people with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) can safely increase their dose of the drug venetoclax faster than the usual 5-week schedule. About 40 participants with newly diagnosed or returning disease will be grouped by their risk of tumor lysis syndrome, a potential side effect. The goal is to find the safest fastest ramp-up and see how well the treatment controls the cancer.

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Conditions

The condition(s) this trial relates to.

B-cell chronic lymphocytic leukemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Dana-Farber Cancer Institute

    Boston, Massachusetts, 02215, United States