Experimental HER2 drug trial halted early – what we know

NCT ID NCT05013554

First seen Nov 01, 2025 · Last updated May 08, 2026 · Updated 29 times

Summary

This early-stage trial tested a new drug called SAR443216 in 44 adults with advanced HER2-positive cancers (like breast, lung, or stomach cancer) that had stopped responding to standard treatments. The main goals were to check safety and find the right dose. The study was terminated early, so results are limited, but it aimed to see if the drug could shrink tumors or slow disease progression.

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Contacts and locations

Locations

  • Investigational Site Number : 0560002

    Ghent, 9000, Belgium

  • Investigational Site Number : 1580001

    Taichung, 404, Taiwan

  • Investigational Site Number : 1580002

    Tainan, 704, Taiwan

  • Investigational Site Number : 2500001

    Pierre-Bénite, 69495, France

  • Investigational Site Number : 2500002

    Villejuif, 94800, France

  • Investigational Site Number : 4100001

    Seoul, Seoul-teukbyeolsi, 03080, South Korea

  • Investigational Site Number : 4100002

    Seoul, Seoul-teukbyeolsi, 05505, South Korea

  • Investigational Site Number : 7240001

    Madrid, Madrid, Comunidad de, 28040, Spain

  • Investigational Site Number : 7240002

    Madrid / Madrid, Madrid, Comunidad de, 28050, Spain

  • Investigational Site Number : 7240003

    Barcelona, Barcelona [Barcelona], 08035, Spain

  • ~University of Texas - MD Anderson Cancer Center Site Number : 8400002

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.