New drug SAL0140 aims to tame Hormone-Driven high blood pressure
NCT ID NCT07646535
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This phase 2 trial tests a new drug called SAL0140 in 50 adults with primary aldosteronism, a condition where the adrenal glands make too much aldosterone, causing high blood pressure. Participants will receive either SAL0140 or a placebo for 12 weeks to see if it safely lowers blood pressure. The study is not yet recruiting.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- SAL0140
- What this could lead to
- If it works, this could lead to a new treatment option for people with primary aldosteronism to better control their blood pressure.
- What could go wrong
- This is an early phase 2 trial with only 50 people, so results may not apply to everyone. The drug may not work better than placebo or could have side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine
Shanghai, Shanghai Municipality, 200025, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- New scan could replace risky vein test for Hormone-Driven high blood pressure
- New screening strategy could speed diagnosis of inherited aldosteronism
- Alcohol injection into adrenal tumors may offer surgery-free blood pressure control
- Sharper blood test could uncover hidden cause of high blood pressure
- New drug may offer safer option for Hormone-Driven high blood pressure